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1

Artificial intelligence in digital pathology — new tools for diagnosis and precision oncology

Bera, Kaustav, Schalper, Kurt A., Rimm, David L., Velcheti, Vamsidhar, Madabhushi, Anant

Journal:

Nature Reviews Clinical Oncology (formerly Nature Clinical Practice Oncology)

Year:

2019

File:

PDF, 7.76 MB

2019

2

EZH2 Inhibitors: Take It EZy, It Is All About Context

Velcheti, Vamsidhar, Wong, Kwok-Kin, Saunthararajah, Yogen

Journal:

Cancer Discovery

Year:

2019

File:

PDF, 11.22 MB

2019

3

Quantitative Assessment of the Heterogeneity of PD-L1 Expression in Non–Small-Cell Lung Cancer

McLaughlin, Joseph, Han, Gang, Schalper, Kurt A., Carvajal-Hausdorf, Daniel, Pelekanou, Vasiliki, Rehman, Jamaal, Velcheti, Vamsidhar, Herbst, Roy, LoRusso, Patricia, Rimm, David L.

Journal:

Year:

2015

Language:

english

File:

PDF, 644 KB

english, 2015

4

Dabrafenib in combination with trametinib in the treatment of patients with BRAF V600-positive advanced or metastatic non-small cell lung cancer: clinical evidence and experience

Khunger, Arjun, Khunger, Monica, Velcheti, Vamsidhar

Journal:

Therapeutic Advances in Respiratory Disease

Year:

2018

Language:

english

File:

PDF, 143 KB

english, 2018

5

P2.04-17 Pre-Therapy Radiomic Features Can Distinguish Hyperprogression from Other Response Patterns to PD1/PD-L1 Inhibitors in NSCLC

Patil, P., Bera, K., Vaidya, P., Khorrami, M., Jain, P., Madabhushi, A., Velcheti, V.

Journal:

Journal of Thoracic Oncology

Year:

2018

Language:

english

File:

PDF, 141 KB

english, 2018

6

An integrated segmentation and shape based classification scheme for distinguishing adenocarcinomas from granulomas on lung CT

Alilou, Mehdi, Beig, Niha, Orooji, Mahdi, Rajiah, Prabhakar, Velcheti, Vamsidhar, Rakshit, Sagar, Reddy, Niyoti, Yang, Michael, Jacono, Frank, Gilkeson, Robert C, Linden, Philip, Madabhushi, Anant

Journal:

Medical Physics

Year:

2017

Language:

english

File:

PDF, 1.95 MB

english, 2017

7

Challenges faced when identifying patients for combination immunotherapy

Ernstoff, Marc S, Gandhi, Shipra, Pandey, Manu, Puzanov, Igor, Grivas, Petros, Montero, Alberto, Velcheti, Vamsidhar, Turk, Mary Jo, Diaz-Montero, Claudia Marcela, Lewis, Lionel D, Morrison, Carl

Journal:

Future Oncology

Year:

2017

Language:

english

File:

PDF, 2.01 MB

english, 2017

8

Safety and efficacy of PD-1/PD-L1 inhibitors in treatment naïve and chemotherapy refractory patients with Non-small cell lung cancer: a systematic review and meta-analysis

Khunger, Monica, Jain, Prantesh, Rakshit, Sagar, Pasupuleti, Vinay, Hernandez, Adrian V., Stevenson, James, Pennell, Nathan A., Velcheti, Vamsidhar

Journal:

Clinical Lung Cancer

Year:

2018

Language:

english

File:

PDF, 2.41 MB

english, 2018

9

Programmed death-1/programmed death-1 ligand axis as a therapeutic target in oncology: current insights

Velcheti, Vamsidhar, Schalper, Kurt, Venur, Vyshak

Journal:

Journal of Receptor Ligand and Channel Research

Year:

2014

Language:

english

File:

PDF, 884 KB

english, 2014

10

51OFirst-line pembrolizumab monotherapy in metastatic PD-L1 positive non-small cell lung cancer: A real-world analysis of time on treatment in US community oncology practices

Velcheti, V, Chandwani, S, Chen, X, Pietanza, M C, Burke, T

Journal:

Annals of Oncology

Year:

2018

Language:

english

File:

PDF, 80 KB

english, 2018

11

P2.16-17 Real-World Trends in Systemic Therapy for Nonsquamous EGFR/ALK-Negative Advanced NSCLC (aNSCLC) in the US, 2011–2018

Velcheti, V., Chandwani, S., Chen, X., Piperdi, B., Burke, T.

Journal:

Journal of Thoracic Oncology

Year:

2019

Language:

english

File:

PDF, 419 KB

english, 2019

12

Objective Measurement and Clinical Significance of TILs in Non-Small Cell Lung Cancer

Schalper, K. A., Brown, J., Carvajal-Hausdorf, D., McLaughlin, J., Velcheti, V., Syrigos, K. N., Herbst, R. S., Rimm, D. L.

Journal:

JNCI Journal of the National Cancer Institute

Year:

2015

Language:

english

File:

PDF, 27.86 MB

english, 2015

13

Changes in Computer Extracted Features of Vessel Tortuosity on CT Scans Post-Treatment in Responders Compared to Non-Responders for Non–Small Cell Lung Cancer on Immunotherapy

Velcheti, V., Alilou, M., Khunger, M., Thawani, R., Madabhushi, A.

Journal:

Journal of Thoracic Oncology

Year:

2017

Language:

english

File:

PDF, 219 KB

english, 2017

14

PUB082 Radiomic Features on Baseline CT Are Predictive of Recurrence in Early Stage Non-Small Cell Lung Cancer Patients

Vaidya, P., Patil, P., Choi, H., Velcheti, V., Madabhushi, A.

Journal:

Journal of Thoracic Oncology

Year:

2017

Language:

english

File:

PDF, 478 KB

english, 2017

15

Post-treatment changes in hematological parameters predict response to nivolumab monotherapy in non-small cell lung cancer patients

Khunger, Monica, Patil, Pradnya Dinkar, Khunger, Arjun, Li, Manshi, Hu, Bo, Rakshit, Sagar, Basu, Arnab, Pennell, Nathan, Stevenson, James P., Elson, Paul, Panchabhai, Tanmay S., Velcheti, Vamsidhar,

Journal:

Year:

2018

Language:

english

File:

PDF, 1.41 MB

english, 2018

16

Programmed death ligand-1 expression in non-small cell lung cancer

Velcheti, Vamsidhar, Schalper, Kurt A, Carvajal, Daniel E, Anagnostou, Valsamo K, Syrigos, Konstantinos N, Sznol, Mario, Herbst, Roy S, Gettinger, Scott N, Chen, Lieping, Rimm, David L

Journal:

Laboratory Investigation

Year:

2014

Language:

english

File:

PDF, 498 KB

english, 2014

17

The Proportion of Patients with Metastatic Non-small Cell Lung Cancer Potentially Eligible for Treatment with Bevacizumab: A Single Institutional Survey

Velcheti, Vamsidhar, Viswanathan, Avinash, Govindan, Ramaswamy

Journal:

Journal of Thoracic Oncology

Year:

2006

Language:

english

File:

PDF, 38 KB

english, 2006

18

Prediction of recurrence in early stage non-small cell lung cancer using computer extracted nuclear features from digital H&E images

Wang, Xiangxue, Janowczyk, Andrew, Zhou, Yu, Thawani, Rajat, Fu, Pingfu, Schalper, Kurt, Velcheti, Vamsidhar, Madabhushi, Anant

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 1.93 MB

english, 2017

19

A Phase 2 Study of Lenvatinib in Patients With RET Fusion-Positive Lung Adenocarcinoma

Hida, Toyoaki, Velcheti, Vamsidhar, Reckamp, Karen L., Nokihara, Hiroshi, Sachdev, Pallavi, Kubota, Tomoki, Nakada, Takuya, Dutcus, Corina E., Ren, Min, Tamura, Tomohide

Journal:

Year:

2019

Language:

english

File:

PDF, 2.84 MB

english, 2019

20

1027MO ALKS 4230 monotherapy and in combination with pembrolizumab (pembro) in patients (pts) with refractory solid tumours (ARTISTRY-1)

Vaishampayan, U.N., Muzaffar, J., Velcheti, V., Winer, I., Hoimes, C.J., Rosen, S.D., Spreafico, A., McDermott, D.F., Chu, Q.S-C., Dumas, O., Gilbert, L., Hirte, H., Curtis, K.K., Du, Y., Bidollari, I

Journal:

Annals of Oncology

Year:

2020

File:

PDF, 109 KB

2020

21

Cost-Effectiveness of Pembrolizumab vs. Docetaxel for Treatment of Previously Treated PD-l1 Positive Advanced NSCLC Patients

Huang, M, Lou, Y, Pellissier, J, Burke, T, Liu, FX, Xu, R, Velcheti,

Journal:

Value in Health

Year:

2016

Language:

english

File:

PDF, 71 KB

english, 2016

22

Absence of Mutations in the Epidermal Growth Factor Receptor (EGFR) Kinase Domain in Patients with Mesothelioma

Velcheti, Vamsidhar, Kasai, Yumi, Viswanathan, Avinash K., Ritter, Jon, Govindan, Ramaswamy

Journal:

Journal of Thoracic Oncology

Year:

2009

Language:

english

File:

PDF, 88 KB

english, 2009

23

Durvalumab in Combination with Olaparib in Patients with Relapsed SCLC: Results from a Phase II Study

Thomas, Anish, Vilimas, Rasa, Trindade, Christopher, Erwin-Cohen, Rebecca, Roper, Nitin, Xi, Liqiang, Krishnasamy, Venkatesh, Levy, Elliot, Mammen, Andy, Nichols, Samantha, Chen, Yuanbin, Velcheti, Va

Journal:

Journal of Thoracic Oncology

Year:

2019

Language:

english

File:

PDF, 1.83 MB

english, 2019

24

PS01.54: Evaluation of Novel Blood-Based Biomarkers with Atezolizumab Monotherapy in 1L Advanced or Metastatic NSCLC (B-F1RST)

Socinski, Mark A., Schiller, Joan, Dakhil, Shaker, Kazmi, Shayma, Leach, Joseph, Hu, Sylvia, Paul, Sarah M., Shames, David S., Phan, See, Yun, Cindy, Velcheti, Vamsidhar

Journal:

Journal of Thoracic Oncology

Year:

2016

Language:

english

File:

PDF, 100 KB

english, 2016

25

Predicting pathologic response to neoadjuvant chemoradiation in resectable stage III non-small cell lung cancer patients using computed tomography radiomic features

Khorrami, Mohammadhadi, Jain, Prantesh, Bera, Kaustav, Patil, Pradnya, Ahmad, Usman, Murthy, Sudish, Stephans, Kevin, Fu, Pingfu, Velcheti, Vamsidhar, Madabhushi, Anant

Journal:

Year:

2019

Language:

english

File:

PDF, 966 KB

english, 2019

26

MA11.03 Interaction of Tumor Infiltrating Lymphocytes and Cancer Nuclei Predicts Response to Nivolumab in Non-Small Cell Lung Cancer (NSCLC)

Wang, X., Barrera, C., Lu, C., Velcheti, V., Madabhushi, A.

Journal:

Journal of Thoracic Oncology

Year:

2018

File:

PDF, 166 KB

2018

27

80PAnti-GITR agonist TRX518 in combination with gemcitabine in advanced solid cancers: Preliminary safety and efficacy from a multi-center phase Ib trial

Velcheti, V, Bauer, T, Luke, J, Rixe, O, Bajor, D, Naik, G S, Sirard, C, Davar, D

Journal:

Annals of Oncology

Year:

2018

File:

PDF, 80 KB

2018

28

P2.04-16 Novel CT Based Radiomic Features are Prognostic and Predictive of Benefit of Chemoimmunotherapy in Advanced Non-Squamous NSCLC

Patil, P., Khorrami, M., Zagouras, A., Bera, K., Fu, P., Gupta, A., Velcheti, V., Pennell, N., Madabhushi, A.

Journal:

Journal of Thoracic Oncology

Year:

2019

Language:

english

File:

PDF, 417 KB

english, 2019

29

P2.16-17 Real-World Trends in Systemic Therapy for Nonsquamous EGFR/ALK-Negative Advanced NSCLC (aNSCLC) in the US, 2011–2018

Velcheti, V., Chandwani, S., Chen, X., Piperdi, B., Burke, T.

Journal:

Journal of Thoracic Oncology

Year:

2019

File:

PDF, 419 KB

2019

30

Novel EGFR Exon 18 (G721R) Mutation in a Patient with Non–Small Cell Lung Carcinoma with Lack of Response to Afatinib

Velcheti, Vamsidhar, Khunger, Monica, Abazeed, Mohamed E.

Journal:

Journal of Thoracic Oncology

Year:

2017

Language:

english

File:

PDF, 573 KB

english, 2017

31

P3.16-10 Radiomic Features on CT are Prognostic of Recurrence as well as Predictive of Added Benefit of Adjuvant Chemotherapy in ES-NSCLC

Vaidya, P., Bera, K., Fu, P., Ganesan, S., Khunger, A., Patil, P., Velcheti, V., Madabhushi, A.

Journal:

Journal of Thoracic Oncology

Year:

2018

Language:

english

File:

PDF, 424 KB

english, 2018

32

Insulin-Like Growth Factor and Lung Cancer

Velcheti, Vamsidhar, Govindan, Ramaswamy

Journal:

Journal of Thoracic Oncology

Year:

2006

Language:

english

File:

PDF, 493 KB

english, 2006

33

Corrigendum to “Predicting pathologic response to neoadjuvant chemoradiation in resectable stage III non-small cell lung cancer patients using computed tomography radiomic features” [Lung Cancer 135 (September) (2019) 1–9]

Khorrami, Mohammadhadi, Jain, Prantesh, Bera, Kaustav, Alilou, Mehdi, Thawani, Rajat, Patil, Pradnya, Ahmad, Usman, Murthy, Sudish, Stephans, Kevin, Fu, Pinfu, Velcheti, Vamsidhar, Madabhushi, Anant

Journal:

Year:

2019

Language:

english

File:

PDF, 137 KB

english, 2019

34

Adjuvant Epithelial Growth Factor Receptor Tyrosine Kinase Inhibitors in Lung Cancer

Davis, Mellar P., Velcheti, Vamsidhar, Pennell, Nathan A.

Journal:

Year:

2016

Language:

english

File:

PDF, 123 KB

english, 2016

35

Programmed death-1/programmed death-1 ligand axis as a therapeutic target in oncology: current insights

Velcheti, Vamsidhar, Schalper, Kurt, Venur, Vyshak

Journal:

Journal of Receptor Ligand and Channel Research

Year:

2014

File:

PDF, 884 KB

2014

36

P1.13-34 Changes in Radiomic Features Between Baseline and Two Weeks Post-Nivolumab Treatment Are Predictive of Pathologic Complete Response

Khorrami, M., Prasanna, P., Corredor-Prada, G., Velcheti, V., Madabhushi, A., Bera, K.

Journal:

Journal of Thoracic Oncology

Year:

2018

Language:

english

File:

PDF, 290 KB

english, 2018

37

Cases from the irAE Tumor Board: A Multidisciplinary Approach to a Patient Treated with Immune Checkpoint Blockade Who Presented with a New Rash

Patil, Pradnya D., Fernandez, Anthony P., Velcheti, Vamsidhar, Tarhini, Ahmad, Funchain, Pauline, Rini, Brian, Khasawneh, Mohamad, Pennell, Nathan A.

Journal:

Year:

2018

Language:

english

File:

PDF, 525 KB

english, 2018

38

Combination of Peri- and Intratumoral Radiomic Features on Baseline CT Scans Predicts Response to Chemotherapy in Lung Adenocarcinoma

Khorrami, Mohammadhadi, Khunger, Monica, Zagouras, Alexia, Patil, Pradnya, Thawani, Rajat, Bera, Kaustav, Rajiah, Prabhakar, Fu, Pingfu, Velcheti, Vamsidhar, Madabhushi, Anant

Journal:

Radiology: Artificial Intelligence

Year:

2019

Language:

english

File:

PDF, 1.04 MB

english, 2019

39

Predicting pathologic response to neoadjuvant chemoradiation in resectable stage III non-small cell lung cancer patients using computed tomography radiomic features

Khorrami, Mohammadhadi, Jain, Prantesh, Bera, Kaustav, Patil, Pradnya, Ahmad, Usman, Murthy, Sudish, Stephans, Kevin, Fu, Pingfu, Velcheti, Vamsidhar, Madabhushi, Anant

Journal:

Year:

2019

File:

PDF, 966 KB

2019

40

P2.16-41 Pembrolizumab for Previously Treated, PD-L1–Expressing Advanced NSCLC: Real-World Time on Treatment and Overall Survival

Velcheti, V., Chandwani, S., Chen, X., Piperdi, B., Burke, T.

Journal:

Journal of Thoracic Oncology

Year:

2019

File:

PDF, 228 KB

2019

41

P2.17-35 Integrating CT Radiomic & Quantitative Histomorphometric Whole Slide Image Features Predicts Disease Free Survival in ES-NSCLC

Vaidya, P., Bera, K., Wang, X., Patil, P., Velcheti, V., Madabhushi, A.

Journal:

Journal of Thoracic Oncology

Year:

2019

File:

PDF, 536 KB

2019

42

Evaluation of PD-L1 expression and Associated Tumor-Infiltrating Lymphocytes in Laryngeal Squamous Cell Carcinoma

Vassilakopoulou, M., Avgeris, M., Velcheti, V., Kotoula, V., Rampias, T., Chatzopoulos, K., Perisanidis, C., Kontos, C. K., Giotakis, A. I., Scorilas, A., Rimm, D. L., Sasaki, C. T., Fountzilas, G., P

Journal:

Clinical Cancer Research

Year:

2015

Language:

english

File:

PDF, 19.93 MB

english, 2015

43

Phase 2 study of lenvatinib in patients with RET fusion-positive adenocarcinoma of the lung

Velcheti, V., Hida, T., Reckamp, K.L., Yang, J.C., Nokihara, H., Sachdev, P., Feit, K., Kubota, T., Nakada, T., Dutcus, C.E., Ren, M., Tamura, T.

Journal:

European Journal of Cancer

Year:

2017

Language:

english

File:

PDF, 50 KB

english, 2017

44

To Treat or Not to Treat: Role of Immunotherapy in Patients with Concomitant Diagnosis of Advanced-Stage Non–Small Cell Lung Cancer and Psoriasis

Khunger, Monica, Calabrese, Cassandra, Kontzias, Apostolos, Velcheti, Vamsidhar

Journal:

Journal of Thoracic Oncology

Year:

2017

Language:

english

File:

PDF, 155 KB

english, 2017

45

Phase I Trial of ALT-803, a Novel Recombinant Interleukin-15 Complex, in Patients with Advanced Solid Tumors

Margolin, Kim, Morishima, Chihiro, Velcheti, Vamsidhar, Miller, Jeffrey S, Lee, Sylvia M., Silk, Ann W., Holtan, Shernan G, Lacroix, Andreanne M., Fling, Steven P, Kaiser, Judith C, Egan, Jack O, Jone

Journal:

Clinical Cancer Research

Year:

2018

Language:

english

File:

PDF, 1.28 MB

english, 2018

46

Quantitative vessel tortuosity: A potential CT imaging biomarker for distinguishing lung granulomas from adenocarcinomas

Alilou, Mehdi, Orooji, Mahdi, Beig, Niha, Prasanna, Prateek, Rajiah, Prabhakar, Donatelli, Christopher, Velcheti, Vamsidhar, Rakshit, Sagar, Yang, Michael, Jacono, Frank, Gilkeson, Robert, Linden, Phi

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 4.25 MB

english, 2018

47

Novel Quantitative Imaging for Predicting Response to Therapy: Techniques and Clinical Applications

Bera, Kaustav, Velcheti, Vamsidhar, Madabhushi, Anant

Journal:

American Society of Clinical Oncology Educational Book

Year:

2018

Language:

english

File:

PDF, 968 KB

english, 2018

48

P2.04-16 Novel CT Based Radiomic Features are Prognostic and Predictive of Benefit of Chemoimmunotherapy in Advanced Non-Squamous NSCLC

Patil, P., Khorrami, M., Zagouras, A., Bera, K., Fu, P., Gupta, A., Velcheti, V., Pennell, N., Madabhushi, A.

Journal:

Journal of Thoracic Oncology

Year:

2019

File:

PDF, 417 KB

2019

49

Checkpoint immunotherapy: good for cancer therapy, bad for rheumatic diseases

Calabrese, Leonard, Velcheti, Vamsidhar

Journal:

Annals of the Rheumatic Diseases

Year:

2017

Language:

english

File:

PDF, 3.48 MB

english, 2017

50

A37 N-803 Plus Nivolumab for Advanced or Metastatic Non-Small Cell Lung Cancer: Update on Phase II Experience of Combination PD1 Blockade with an IL-15 Superagonist

Wrangle, J., Velcheti, V., Patel, M., Sweiderska-syn, M., Macpherson, L., Coggins, C., Kreig, C., Redmond, W., Rock, A., Lee, J., Rubinstein, M.

Journal:

Journal of Thoracic Oncology

Year:

2020

Language:

english

File:

PDF, 203 KB

english, 2020

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